miR-199a-5p Reduces Chondrocyte Hypertrophy and Attenuates Osteoarthritis Progression via the Indian Hedgehog Signal Pathway

miR-199a-5p Reduces Chondrocyte Hypertrophy and Attenuates Osteoarthritis Progression via the Indian Hedgehog Signal Pathway

Osteoarthritis (OA), the most common type of arthritis, is an age-associated disease, characterized by the progressive degradation of articular cartilage, synovial inflammation, and degeneration of subchondral bone. Chondrocyte proliferation is regulated by the Indian hedgehog (IHH in humans, Ihh in...

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Bibliographic Details
Main Authors: Lei Huang, Meng Jin, Ruiying Gu, Kunlin Xiao, Mengnan Lu, Xinyu Huo, Mengyao Sun, Zhi Yang, Zhiyuan Wang, Weijie Zhang, Liqiang Zhi, Ziang Meng, Jie Ma, Jianbing Ma, Rui Zhang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Clinical Medicine
Subjects:
miR-199a-5p
osteoarthritis
cartilage
chondrocyte
intra-articular injection
Online Access:https://www.mdpi.com/2077-0383/12/4/1313

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https://www.mdpi.com/2077-0383/12/4/1313

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