Hydrogel‐Sheathed hiPSC‐Derived Heart Microtissue Enables Anchor‐Free Contractile Force Measurement

Hydrogel‐Sheathed hiPSC‐Derived Heart Microtissue Enables Anchor‐Free Contractile Force Measurement

Abstract In vitro reconstruction of highly mature engineered heart tissues (EHTs) is attempted for the selection of cardiotoxic drugs suitable for individual patients before administration. Mechanical contractile force generated in the EHTs is known to be a critical indicator for evaluating the EHT...

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Bibliographic Details
Main Authors: Yuta Kurashina, Keisuke Fukada, Shun Itai, Shuichi Akizuki, Ryo Sato, Akari Masuda, Hidenori Tani, Jun Fujita, Keiichi Fukuda, Shugo Tohyama, Hiroaki Onoe
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Advanced Science
Subjects:
anchor‐free
contractile force
engineered heart microtissue
hiPSC‐derived cardiomyocytes
hydrogel
Online Access:https://doi.org/10.1002/advs.202301831

Internet

https://doi.org/10.1002/advs.202301831

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