Prdm8 regulates the morphological transition at multipolar phase during neocortical development.

Here, we found that the PR domain protein Prdm8 serves as a key regulator of the length of the multipolar phase by controlling the timing of morphological transition. We used a mouse line with expression of Prdm8-mVenus reporter and found that Prdm8 is predominantly expressed in the middle and upper...

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Bibliographic Details
Main Authors: Mayuko Inoue, Takao Kuroda, Aya Honda, Mariko Komabayashi-Suzuki, Tae Komai, Yoichi Shinkai, Ken-ichi Mizutani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24489718/pdf/?tool=EBI