The synergism of SMC1A cohesin gene silencing and bevacizumab against colorectal cancer

The synergism of SMC1A cohesin gene silencing and bevacizumab against colorectal cancer

Abstract Background SMC1A is a subunit of the cohesin complex that participates in many DNA- and chromosome-related biological processes. Previous studies have established that SMC1A is involved in cancer development and in particular, is overexpressed in chromosomally unstable human colorectal canc...

Full description

Bibliographic Details
Main Authors: Maddalena Di Nardo, Simonetta Astigiano, Silvia Baldari, Maria Michela Pallotta, Giovanni Porta, Simona Pigozzi, Annalisa Antonini, Laura Emionite, Annalisa Frattini, Roberto Valli, Gabriele Toietta, Silvia Soddu, Antonio Musio
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Cohesin
SMC1A
shRNA
Bevacizumab
Colorectal cancer
Gene expression dysregulation
Online Access:https://doi.org/10.1186/s13046-024-02976-2

Internet

https://doi.org/10.1186/s13046-024-02976-2

Similar Items