The synergism of SMC1A cohesin gene silencing and bevacizumab against colorectal cancer

The synergism of SMC1A cohesin gene silencing and bevacizumab against colorectal cancer

Abstract Background SMC1A is a subunit of the cohesin complex that participates in many DNA- and chromosome-related biological processes. Previous studies have established that SMC1A is involved in cancer development and in particular, is overexpressed in chromosomally unstable human colorectal canc...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Maddalena Di Nardo, Simonetta Astigiano, Silvia Baldari, Maria Michela Pallotta, Giovanni Porta, Simona Pigozzi, Annalisa Antonini, Laura Emionite, Annalisa Frattini, Roberto Valli, Gabriele Toietta, Silvia Soddu, Antonio Musio
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2024-02-01
Schriftenreihe:Journal of Experimental & Clinical Cancer Research
Schlagworte:
Cohesin
SMC1A
shRNA
Bevacizumab
Colorectal cancer
Gene expression dysregulation
Online Zugang:https://doi.org/10.1186/s13046-024-02976-2

Online

https://doi.org/10.1186/s13046-024-02976-2

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