Investigations into the Potential Role of Metabolites on the Anti-Leukemic Activity of Imatinib, Nilotinib and Midostaurin

The efficacy and side-effects of drugs do not just reflect the biochemical and pharmacodynamic properties of the parent compound, but often comprise of cooperative effects between the properties of the parent and active metabolites. Metabolites of imatinib, nilotinib and midostaurin have b...

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Bibliographic Details
Main Author: Paul W. Manley
Format: Article
Language:deu
Published: Swiss Chemical Society 2019-08-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/1280