Hydroxycoumarin Scopoletin Inhibits Bone Loss through Enhancing Induction of Bone Turnover Markers in a Mouse Model of Type 2 Diabetes

Hydroxycoumarin Scopoletin Inhibits Bone Loss through Enhancing Induction of Bone Turnover Markers in a Mouse Model of Type 2 Diabetes

Diabetes induces bone deterioration, which leads to increased risk of fracture, osteopenia, and osteoporosis. Thus, diabetes-associated bone fragility has been recognized as a diabetic complication. However, the pathophysiological effects of hyperglycemia on bone turnover remain unclear. Literature...

Full description

Bibliographic Details
Main Authors: Eun-Jung Lee, Woojin Na, Min-Kyung Kang, Yun-Ho Kim, Dong-Yeon Kim, Hyeongjoo Oh, Soo-Il Kim, Su-Yeon Oh, Sohyun Park, Kyungho Park, Young-Hee Kang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
bone remodeling
bone turnover
osteoblasts
osteoclasts
scopoletin
type 2 diabetes
Online Access:https://www.mdpi.com/2227-9059/9/6/648

Internet

https://www.mdpi.com/2227-9059/9/6/648

Similar Items