Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity

Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity

The endocannabinoid system represents an integrated neuronal network involved in the control of several organisms&#8217; functions, such as feeding behavior. A series of hybrids of 5-(4-chlorophenyl)-1-(2,4-dichloro-phenyl)-4-methyl-<i>N</i>-(piperidin-1-yl)-1<i>H</i>-pyr...

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Bibliographic Details
Main Authors: Marilisa P. Dimmito, Azzurra Stefanucci, Stefano Pieretti, Paola Minosi, Szabolcs Dvorácskó, Csaba Tömböly, Gokhan Zengin, Adriano Mollica
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Biomolecules
Subjects:
cannabinoid receptor
rimonabant
food intake
anorexant agent
edema
Online Access:https://www.mdpi.com/2218-273X/9/9/492

Internet

https://www.mdpi.com/2218-273X/9/9/492

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