Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids

Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids

Summary: Uterine fibroids are benign myometrial smooth muscle tumors of unknown etiology that, when symptomatic, are the most common indication for hysterectomy in the United States. Unsupervised clustering of results from DNA methylation analyses segregates normal myometrium from fibroids and furth...

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Bibliographic Details
Main Authors: Jitu Wilson George, Huihui Fan, Benjamin Johnson, Tyler James Carpenter, Kelly Katherine Foy, Anindita Chatterjee, Amanda Lynn Patterson, Julie Koeman, Marie Adams, Zachary Brian Madaj, David Chesla, Erica Elizabeth Marsh, Timothy Junius Triche, Hui Shen, Jose Manuel Teixeira
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719315682

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http://www.sciencedirect.com/science/article/pii/S2211124719315682

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