Exogenous Nitric Oxide Up-regulates the Runx2 Via Bmp7 Overexpression to Increase the Osteoblast Matrix Production In Vitro

Background: Nitric oxide (NO) is a signaling molecule that is required for the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). According to previous reports, high concentrations of sodium nitroprusside (SNP) inhibit the osteogenic differentiation of BMSCs, while its low con...

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Bibliographic Details
Main Authors: Mohammad Hussein Abnos, Javad Sargolzaei, Mahsa Maleklou
Format: Article
Language:English
Published: Hamadan University of Medical Sciences 2022-06-01
Series:Avicenna Journal of Medical Biochemistry
Subjects:
Online Access:http://ajmb.umsha.ac.ir/PDF/ajmb-10-58.pdf