A Salmonella Typhimurium-Typhi genomic chimera: a model to study Vi polysaccharide capsule function in vivo.

The Vi capsular polysaccharide is a virulence-associated factor expressed by Salmonella enterica serotype Typhi but absent from virtually all other Salmonella serotypes. In order to study this determinant in vivo, we characterised a Vi-positive S. Typhimurium (C5.507 Vi(+)), harbouring the Salmonell...

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Bibliographic Details
Main Authors: Angela M Jansen, Lindsay J Hall, Simon Clare, David Goulding, Kathryn E Holt, Andrew J Grant, Piero Mastroeni, Gordon Dougan, Robert A Kingsley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21829346/?tool=EBI