Intestinal gluconeogenesis is downregulated in pediatric patients with celiac disease

Abstract Background Untreated celiac disease (CD) patients have increased levels of blood glutamine and a lower duodenal expression of glutaminase (GLS). Intestinal gluconeogenesis (IGN) is a process through which glutamine is turned into glucose in the small intestine, for which GLS is crucial. Ani...

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Bibliographic Details
Main Authors: Olof Karlson, Henrik Arnell, Audur H. Gudjonsdottir, Daniel Agardh, Åsa Torinsson Naluai
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12916-022-02635-3