CD24 Is a Potential Immunotherapeutic Target for Mantle Cell Lymphoma

CD24 Is a Potential Immunotherapeutic Target for Mantle Cell Lymphoma

CD24 and its ligand Siglec-10 were described as an innate immune checkpoint in carcinoma. Here, we investigated this axis in B-cell lymphoma by assessing CD24 expression and evaluating pro-phagocytic effects of CD24 antibody treatment in comparison to hallmark immune checkpoint CD47. In mantle cell...

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Bibliographic Details
Main Authors: Jimena Álvarez Freile, Natasha Ustyanovska Avtenyuk, Macarena González Corrales, Harm Jan Lourens, Gerwin Huls, Tom van Meerten, Ewa Cendrowicz, Edwin Bremer
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
mantle cell lymphoma
CD24
immunotherapy
immune checkpoint
phagocytosis
Online Access:https://www.mdpi.com/2227-9059/10/5/1175

Internet

https://www.mdpi.com/2227-9059/10/5/1175

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