Functional Genomic Screening in Human Pluripotent Stem Cells Reveals New Roadblocks in Early Pancreatic Endoderm Formation

Functional Genomic Screening in Human Pluripotent Stem Cells Reveals New Roadblocks in Early Pancreatic Endoderm Formation

Human pluripotent stem cells, with their ability to proliferate indefinitely and to differentiate into virtually all cell types of the human body, provide a novel resource to study human development and to implement relevant disease models. Here, we employed a human pancreatic differentiation platfo...

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Bibliographic Details
Main Authors: Jana Krüger, Markus Breunig, Lino Pascal Pasquini, Mareen Morawe, Alexander Groß, Frank Arnold, Ronan Russell, Thomas Seufferlein, Ninel Azoitei, Hans A. Kestler, Cécile Julier, Sandra Heller, Meike Hohwieler, Alexander Kleger
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
stem cells
pancreatic development
definitive endoderm
shRNA
Online Access:https://www.mdpi.com/2073-4409/11/3/582

Internet

https://www.mdpi.com/2073-4409/11/3/582

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