Soluble CD40 Ligand and Oxidative Response Are Reciprocally Stimulated during Shiga Toxin-Associated Hemolytic Uremic Syndrome

Soluble CD40 Ligand and Oxidative Response Are Reciprocally Stimulated during Shiga Toxin-Associated Hemolytic Uremic Syndrome

Shiga toxin (Stx), produced by Escherichia coli, is the main pathogenic factor of diarrhea-associated hemolytic uremic syndrome (HUS), which is characterized by the obstruction of renal microvasculature by platelet-fibrin thrombi. It is well known that the oxidative imbalance generated by Stx induce...

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Bibliographic Details
Main Authors: Maria J. Abrey Recalde, Romina S. Alvarez, Fabiana Alberto, Maria P. Mejias, Maria V. Ramos, Romina J. Fernandez Brando, Andrea C. Bruballa, Ramon A. Exeni, Laura Alconcher, Cristina A. Ibarra, María M. Amaral, Marina S. Palermo
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Toxins
Subjects:
hemolytic uremic syndrome
oxidative stress
blood platelets
Shiga toxin 2
CD40L
Online Access:https://www.mdpi.com/2072-6651/9/11/331

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https://www.mdpi.com/2072-6651/9/11/331

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