WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation

WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation

Abstract Background Congenital heart disease (CHD) is the most common birth defect and has high heritability. Although some susceptibility genes have been identified, the genetic basis underlying the majority of CHD cases is still undefined. Methods A total of 1320 unrelated CHD patients were enroll...

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Bibliographic Details
Main Authors: Lili Hao, Jing Ma, Feizhen Wu, Xiaojing Ma, Maoxiang Qian, Wei Sheng, Tizhen Yan, Ning Tang, Xin Jiang, Bowen Zhang, Deyong Xiao, Yanyan Qian, Jin Zhang, Nan Jiang, Wenhao Zhou, Weicheng Chen, Duan Ma, Guoying Huang
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Clinical and Translational Medicine
Subjects:
cardiomyocyte proliferation
cell cycle
congenital heart disease
spindle assembly
the WDR62 gene
Online Access:https://doi.org/10.1002/ctm2.941

Internet

https://doi.org/10.1002/ctm2.941

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