Identification of Novel Dopamine D<sub>2</sub> Receptor Ligands—A Combined In Silico/In Vitro Approach

Identification of Novel Dopamine D<sub>2</sub> Receptor Ligands—A Combined In Silico/In Vitro Approach

Diseases of the central nervous system are an alarming global problem showing an increasing prevalence. Dopamine receptor D<sub>2</sub> (D<sub>2</sub>R) has been shown to be involved in central nervous system diseases. While different D<sub>2</sub>R-targeting drug...

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Bibliographic Details
Main Authors: Lukas Zell, Constanze Lainer, Jakub Kollár, Veronika Temml, Daniela Schuster
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
dopamine receptor
GPCR
in silico
pharmacophore modelling
virtual screening
in vitro
Online Access:https://www.mdpi.com/1420-3049/27/14/4435

Internet

https://www.mdpi.com/1420-3049/27/14/4435

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