Epidermal Growth Factor Receptor Expression and Resistance Patterns to Targeted Therapy in Non-Small Cell Lung Cancer: A Review

Epidermal Growth Factor Receptor Expression and Resistance Patterns to Targeted Therapy in Non-Small Cell Lung Cancer: A Review

Globally, lung cancer is the leading cause of cancer-related death. The majority of non-small cell lung cancer (NSCLC) tumours express epidermal growth factor receptor (EGFR), which allows for precise and targeted therapy in these patients. The dysregulation of EGFR in solid epithelial cancers has t...

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Bibliographic Details
Main Authors: Emma-Anne Karlsen, Sam Kahler, Joan Tefay, Shannon R. Joseph, Fiona Simpson
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
epidermal growth factor receptor
non-small cell lung cancer
drug resistance
tyrosine kinase inhibitor
monoclonal antibody
Online Access:https://www.mdpi.com/2073-4409/10/5/1206

Internet

https://www.mdpi.com/2073-4409/10/5/1206

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