Temporal transcriptome features identify early skeletal commitment during human epiphysis development at single-cell resolution

Summary: Human epiphyseal development has been mainly investigated through radiological and histological approaches, uncovering few details of cellular temporal genetic alternations. Using single-cell RNA sequencing, we investigated the dynamic transcriptome changes during post-conception weeks (PCW...

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Bibliographic Details
Main Authors: Zhonghao Deng, Shengwei Rong, Lu Gan, Fuhua Wang, Liangxiao Bao, Fang Cai, Zheting Liao, Yu Jin, Shuhao Feng, Zihang Feng, Yiran Wei, Ruge Chen, Yangchen Jin, Yanli Zhou, Xiaoyong Zheng, Liping Huang, Liang Zhao
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012774