Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice

Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice

Pancreatic ductal adenocarcinoma (PDAC) will soon belong to the top three cancer killers. The only approved specific PDAC therapy targets the epidermal growth factor receptor (EGFR). Although EGFR is a crucial player in PDAC development, EGFR‐based therapy is disappointing. In this study, we evaluat...

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Bibliographic Details
Main Authors: Kathrin Hedegger, Hana Algül, Marina Lesina, Andreas Blutke, Roland M. Schmid, Marlon R. Schneider, Maik Dahlhoff
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Molecular Oncology
Subjects:
BTC
EGFR
ERBB2
ERBB4
mouse model
PDAC
Online Access:https://doi.org/10.1002/1878-0261.12699

Internet

https://doi.org/10.1002/1878-0261.12699

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