A novel antibiotic combination of linezolid and polymyxin B octapeptide PBOP against clinical Pseudomonas aeruginosa strains

A novel antibiotic combination of linezolid and polymyxin B octapeptide PBOP against clinical Pseudomonas aeruginosa strains

Abstract Background Antibiotic-resistant Gram-negative bacteria are becoming a major public health threat such as the important opportunistic pathogen Pseudomonas aeruginosa (P. aeruginosa). The present study investigated enhancement of the linezolid spectrum, which is normally used to treat Gram-po...

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Bibliographic Details
Main Authors: Ting Huang, Mao Zeng, Huiyao Fu, Kelei Zhao, Tao Song, Yidong Guo, Jingyu Zhou, Longfei Zhai, Chaolan Liu, Balakrishnan Prithiviraj, Xinrong Wang, Yiwen Chu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Polymyxin B octapeptide
Linezolid
Antibacterial activity
Synergistic effect
Pseudomonas aeruginosa
Online Access:https://doi.org/10.1186/s12941-022-00531-5

Internet

https://doi.org/10.1186/s12941-022-00531-5

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