Exploring the neuroprotection of the combination of astragaloside A, chlorogenic acid and scutellarin in treating chronic cerebral ischemia via network analysis and experimental validation

Exploring the neuroprotection of the combination of astragaloside A, chlorogenic acid and scutellarin in treating chronic cerebral ischemia via network analysis and experimental validation

Chronic cerebral ischemia (CCI) primarily causes cognitive dysfunction and other neurological impairments, yet there remains a lack of ideal therapeutic medications. The preparation combination of Astragalus membranaceus (Fisch.) Bunge and Erigeron breviscapus (Vant.) Hand.-Mazz have been utilized t...

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Bibliographic Details
Main Authors: Fang Cheng, Jie Zhang, Pan Yang, Zufei Chen, Yinghao Fu, Jiajia Mi, Xingliang Xie, Sha Liu, Yanmei Sheng
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Chronic cerebral ischemia
Astragaloside A
Chlorogenic acid and scutellarin combination
Network analysis
PI3K/AKT pathway
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024051934

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http://www.sciencedirect.com/science/article/pii/S2405844024051934

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