Rapid activation of Rac GTPase in living cells by force is independent of Src.

It is well known that mechanical forces are crucial in regulating functions of every tissue and organ in a human body. However, it remains unclear how mechanical forces are transduced into biochemical activities and biological responses at the cellular and molecular level. Using the magnetic twistin...

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Bibliographic Details
Main Authors: Yeh-Chuin Poh, Sungsoo Na, Farhan Chowdhury, Mingxing Ouyang, Yingxiao Wang, Ning Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2773925?pdf=render