Potential utility of amantadine DR/ER in persons with Parkinson’s disease meeting 5-2-1 criteria for device aided therapy

Background: The 5-2-1 criteria (≥5 levodopa doses/day, ≥2 h OFF/day, and ≥ 1-hour dyskinesia/day) propose to identify people with Parkinson’s disease (PD) who are poorly controlled on oral therapies and who may therefore benefit from device-aided therapies. Amantadine-DR/ER is the only medication FD...

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Bibliographic Details
Main Authors: Robert A. Hauser, Santosh Goud, Andrea E. Formella
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Clinical Parkinsonism & Related Disorders
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590112521000359