How the Innate Immune DNA Sensing cGAS–STING Pathway Is Involved in Autophagy

How the Innate Immune DNA Sensing cGAS–STING Pathway Is Involved in Autophagy

The cGAS–STING pathway is a key component of the innate immune system and exerts crucial roles in the detection of cytosolic DNA and invading pathogens. Accumulating evidence suggests that the intrinsic cGAS–STING pathway not only facilitates the production of type I interferons (IFN-I) and inflamma...

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Bibliographic Details
Main Authors: Wanglong Zheng, Nengwen Xia, Jiajia Zhang, Nanhua Chen, François Meurens, Zongping Liu, Jianzhong Zhu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
cGAS
STING
autophagy
innate immunity
IFN
DNA sensing
Online Access:https://www.mdpi.com/1422-0067/22/24/13232

Internet

https://www.mdpi.com/1422-0067/22/24/13232

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