The influence of age, sex, and exercise on autophagy, mitophagy, and lysosome biogenesis in skeletal muscle

Abstract Background Aging decreases skeletal muscle mass and quality. Maintenance of healthy muscle is regulated by a balance between protein and organellar synthesis and their degradation. The autophagy-lysosome system is responsible for the selective degradation of protein aggregates and organelle...

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Bibliographic Details
Main Authors: Matthew Triolo, Ashley N. Oliveira, Rita Kumari, David A. Hood
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Skeletal Muscle
Subjects:
Online Access:https://doi.org/10.1186/s13395-022-00296-7