Novel protein-truncating variant in the APOB gene may protect from coronary artery disease and adverse cardiovascular events

Novel protein-truncating variant in the APOB gene may protect from coronary artery disease and adverse cardiovascular events

Background and aims: Genetic testing is still rarely used for the diagnosis of dyslipidemia, even though gene variants determining plasma lipids levels are not uncommon. Methods: Starting from a a pilot-analysis of targeted Next Generation Sequencing (NGS) of 5 genes related to familial hypercholest...

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Bibliographic Details
Main Authors: Gabriele Mango, Nicola Osti, Silvia Udali, Anna Vareschi, Giovanni Malerba, Alejandro Giorgetti, Francesca Pizzolo, Simonetta Friso, Domenico Girelli, Oliviero Olivieri, Annalisa Castagna, Nicola Martinelli
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Atherosclerosis Plus
Subjects:
Dyslipidemia
Apolipoprotein B
Coronary Artery Disease
Next Generation Sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2667089522000189

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http://www.sciencedirect.com/science/article/pii/S2667089522000189

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