The role of N-glycosylation of CD200-CD200R1 interaction in classical microglial activation

Abstract Background Microglial inflammatory activation is the common feature of the central nervous system (CNS) diseases. Microglia can be activated and particularly polarized toward a dual role in the injured CNS. The CD200 receptor 1 (CD200R1) inhibits inflammatory microglia activation as illustr...

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Bibliographic Details
Main Authors: Chao Liu, Yifen Shen, Ying Tang, Yongchun Gu
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Inflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12950-018-0205-8