Synthesis of New Indole Derivatives Structurally Related to Donepezil and Their Biological Evaluation as Acetylcholinesterase Inhibitors

New series of indole derivatives analogous to donepezil, a well known anti-Alzheimer and acetylcholinesterase inhibitor drug, was synthesized. A full chemical characterization of the new compounds is provided. Biological evaluation of the new compounds as acetylcholinesterase inhibitors was performe...

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Bibliographic Details
Main Authors: Samar I. Faggal, Lamia W. Mohamed, Mona M. Kamel, Mohamed M. Ismail
Format: Article
Language:English
Published: MDPI AG 2012-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/5/4811