Synthesis of New Indole Derivatives Structurally Related to Donepezil and Their Biological Evaluation as Acetylcholinesterase Inhibitors

Synthesis of New Indole Derivatives Structurally Related to Donepezil and Their Biological Evaluation as Acetylcholinesterase Inhibitors

New series of indole derivatives analogous to donepezil, a well known anti-Alzheimer and acetylcholinesterase inhibitor drug, was synthesized. A full chemical characterization of the new compounds is provided. Biological evaluation of the new compounds as acetylcholinesterase inhibitors was performe...

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Bibliographic Details
Main Authors:	Samar I. Faggal, Lamia W. Mohamed, Mona M. Kamel, Mohamed M. Ismail
Format:	Article
Language:	English
Published:	MDPI AG 2012-04-01
Series:	Molecules
Subjects:	indole isatin oxindole acetylcholinesterase inhibitors Alzheimer donepezil
Online Access:	http://www.mdpi.com/1420-3049/17/5/4811

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