Bioinformatic Analysis and Experimental Validation of Ubiquitin-Proteasomal System-Related Hub Genes as Novel Biomarkers for Alzheimer's Disease

Bioinformatic Analysis and Experimental Validation of Ubiquitin-Proteasomal System-Related Hub Genes as Novel Biomarkers for Alzheimer's Disease

Background: Alzheimer’s disease (AD) is a common progressive neurodegenerative disease. The Ubiquitin-Protease system (UPS), which plays important roles in maintaining protein homeostasis in eukaryotic cells, is involved in the development of AD. This study sought to identify differential UPS-relate...

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Bibliographic Details
Main Authors: Yuting Zhang, Jie Wu, Guoxing You, Wenjie Guo, Yupeng Wang, Zhiyong Yu, Yan Geng, Qinghua Zhong, Jie Zan, Linbo Zheng
Format: Article
Language:English
Published: IMR Press 2023-10-01
Series:Journal of Integrative Neuroscience
Subjects:
ad
machine learning
ubiquitin-protease
biomarkers
bioinformatic
Online Access:https://www.imrpress.com/journal/JIN/22/6/10.31083/j.jin2206138

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https://www.imrpress.com/journal/JIN/22/6/10.31083/j.jin2206138

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