Direct digital sensing of protein biomarkers in solution

Direct digital sensing of protein biomarkers in solution

There are limitations with current protein sensing methods. Here the authors report DigitISA, a digital immunosensor assay based on microchip electrophoretic separation and single-molecule detection that enables quantitation of protein biomarkers in a single, solution-phase step.

Bibliographic Details
Main Authors: Georg Krainer, Kadi L. Saar, William E. Arter, Timothy J. Welsh, Magdalena A. Czekalska, Raphaël P. B. Jacquat, Quentin Peter, Walther C. Traberg, Arvind Pujari, Akhila K. Jayaram, Pavankumar Challa, Christopher G. Taylor, Lize-Mari van der Linden, Titus Franzmann, Roisin M. Owens, Simon Alberti, David Klenerman, Tuomas P. J. Knowles
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-35792-x

Internet

https://doi.org/10.1038/s41467-023-35792-x

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