Detection of new pioneer transcription factors as cell-type-specific nucleosome binders

Detection of new pioneer transcription factors as cell-type-specific nucleosome binders

Wrapping of DNA into nucleosomes restricts accessibility to DNA and may affect the recognition of binding motifs by transcription factors. A certain class of transcription factors, the pioneer transcription factors, can specifically recognize their DNA binding sites on nucleosomes, initiate local ch...

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Bibliographic Details
Main Authors: Yunhui Peng, Wei Song, Vladimir B Teif, Ivan Ovcharenko, David Landsman, Anna R Panchenko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Series:eLife
Subjects:
nucleosome
pioneer transcription factor
chromatin
transcription factor
nucleosome binding
computational
Online Access:https://elifesciences.org/articles/88936

Internet

https://elifesciences.org/articles/88936

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