Many Distinct Ways Lead to Drug Resistance in <i>BRAF</i>- and <i>NRAS</i>-Mutated Melanomas
Advanced melanoma is a relentless tumor with a high metastatic potential. The combat of melanoma by using the targeted therapy is impeded because several major driver mutations fuel its growth (predominantly <i>BRAF</i> and <i>NRAS</i>). Both these mutated oncogenes strongly...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
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| Series: | Life |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-1729/11/5/424 |