A Multiple Comprehensive Analysis of scATAC-seq Based on Auto-Encoder and Matrix Decomposition

Single-cell ATAC-seq (scATAC-seq), as the updating of ATAC-seq, provides a novel method for probing open chromatin sites. Currently, research of scATAC-seq is faced with the problem of high dimensionality and the inherent sparsity of the generated data. Recently, several works proposed the use of an...

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Bibliographic Details
Main Authors: Yuyao Huang, Yizhou Li, Yuan Liu, Runyu Jing, Menglong Li
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Symmetry
Subjects:
Online Access:https://www.mdpi.com/2073-8994/13/8/1467