Differential requirement for Hoxa9 in the development and differentiation of B, NK, and DC-lineage cells from Flt3+ multipotential progenitors
<p>Abstract</p> <p>Hoxa9 is a homeodomain transcription factor important for the generation of Flt3+hiIL-7R- lymphoid biased-multipotential progenitors, Flt3+IL-7R+ common lymphoid progenitors (CLPs), and B cell precursors (BCP) in bone marrow (BM). In addition to B-cell, Flt3+IL-7...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2013-01-01
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Series: | BMC Immunology |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2172/14/5 |