Differential requirement for Hoxa9 in the development and differentiation of B, NK, and DC-lineage cells from Flt3+ multipotential progenitors

<p>Abstract</p> <p>Hoxa9 is a homeodomain transcription factor important for the generation of Flt3+hiIL-7R- lymphoid biased-multipotential progenitors, Flt3+IL-7R+ common lymphoid progenitors (CLPs), and B cell precursors (BCP) in bone marrow (BM). In addition to B-cell, Flt3+IL-7...

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Bibliographic Details
Main Authors: Gwin Kimberly, Dolence Joseph J, Shapiro Mariya B, Medina Kay L
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Immunology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2172/14/5