TRAIP resolves DNA replication-transcription conflicts during the S-phase of unperturbed cells

Abstract Cell division is the basis for the propagation of life and requires accurate duplication of all genetic information. DNA damage created during replication (replication stress) is a major cause of cancer, premature aging and a spectrum of other human disorders. Over the years, TRAIP E3 ubiqu...

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Bibliographic Details
Main Authors: Shaun Scaramuzza, Rebecca M. Jones, Martina Muste Sadurni, Alicja Reynolds-Winczura, Divyasree Poovathumkadavil, Abigail Farrell, Toyoaki Natsume, Patricia Rojas, Cyntia Fernandez Cuesta, Masato T. Kanemaki, Marco Saponaro, Agnieszka Gambus
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40695-y