Interleukin-36γ is causative for liver damage upon infection with Rift Valley fever virus in type I interferon receptor-deficient mice

Interleukin-36γ is causative for liver damage upon infection with Rift Valley fever virus in type I interferon receptor-deficient mice

Type I interferons (IFN) are pro-inflammatory cytokines which can also exert anti-inflammatory effects via the regulation of interleukin (IL)-1 family members. Several studies showed that interferon receptor (IFNAR)-deficient mice develop severe liver damage upon treatment with artificial agonists s...

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Bibliographic Details
Main Authors: Martina Anzaghe, Marc A. Niles, Eugenia Korotkova, Monica Dominguez, Stefanie Kronhart, Samira Ortega Iannazzo, Ingo Bechmann, Malte Bachmann, Heiko Mühl, Georg Kochs, Zoe Waibler
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
rift valley fever virus
type I interferon
interleukin-36γ
anti-inflammatory
immune pathology
dysregulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1194733/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1194733/full

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