Erosion of Conserved Binding Sites in Personal Genomes Points to Medical Histories.

Although many human diseases have a genetic component involving many loci, the majority of studies are statistically underpowered to isolate the many contributing variants, raising the question of the existence of alternate processes to identify disease mutations. To address this question, we collec...

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Bibliographic Details
Main Authors: Harendra Guturu, Sandeep Chinchali, Shoa L Clarke, Gill Bejerano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4742230?pdf=render