Metabolic Dysfunctions of Intestinal Fatty Acids and Tryptophan Reveal Immuno-Inflammatory Response Activation in IgA Nephropathy

Metabolic Dysfunctions of Intestinal Fatty Acids and Tryptophan Reveal Immuno-Inflammatory Response Activation in IgA Nephropathy

BackgroundImmunoglobulin A nephropathy (IgAN) is the most common form of primary glomerulonephritis. Although an important link between intestinal metabolites and immune activity is widely established, the metabolic profile of IgAN is still poorly understood, which severely limits the mechanistic st...

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Bibliographic Details
Main Authors: Hongwei Wu, Donge Tang, Manhua Yun, Haiping Liu, Shaoxing Huang, Chen Yun, Berthold Hocher, Xinzhou Zhang, Fanna Liu, Lianghong Yin, Yong Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Medicine
Subjects:
IgA nephropathy
fatty acid metabolism
tryptophan metabolism
immune
3-indolepropionic acid
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.811526/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.811526/full

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