CD81 suppresses NF-κB signaling and is downregulated in hepatitis C virus expressing cells

CD81 suppresses NF-κB signaling and is downregulated in hepatitis C virus expressing cells

The tetraspanin CD81 is one of the main entry receptors for Hepatitis C virus, which is a major causative agent to develop liver cirrhosis and hepatocellular carcinoma (HCC). Here, we identify CD81 as one of few surface proteins that are downregulated in HCV expressing hepatoma cells, discovering a...

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Bibliographic Details
Main Authors: Maximilian Bunz, Mona Eisele, Dan Hu, Michael Ritter, Julia Kammerloher, Sandra Lampl, Michael Schindler
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
hepatitis C virus
hepatocellular carcinoma
HCC
CD81
tetraspanin
NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1338606/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2024.1338606/full

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