Long term N-acetylcysteine administration rescues liver steatosis via endoplasmic reticulum stress with unfolded protein response in mice

Long term N-acetylcysteine administration rescues liver steatosis via endoplasmic reticulum stress with unfolded protein response in mice

Abstract Background Fat accumulation in the liver contributes to the development of non-alcoholic fatty liver disease (NAFLD). N-acetylcysteine (NAC) is an antioxidant, acting both directly and indirectly via upregulation of cellular antioxidants. We examined the mechanisms of liver steatosis after...

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Bibliographic Details
Main Authors: Ching-Chou Tsai, Yu-Jen Chen, Hong-Ren Yu, Li-Tung Huang, You-Lin Tain, I-Chun Lin, Jiunn-Ming Sheen, Pei-Wen Wang, Mao-Meng Tiao
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Lipids in Health and Disease
Subjects:
Acetylcysteine
Steatosis
Liver
ER stress
Online Access:http://link.springer.com/article/10.1186/s12944-020-01274-y

Internet

http://link.springer.com/article/10.1186/s12944-020-01274-y

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