An agent-based model of cardiac allograft vasculopathy: toward a better understanding of chronic rejection dynamics

An agent-based model of cardiac allograft vasculopathy: toward a better understanding of chronic rejection dynamics

Cardiac allograft vasculopathy (CAV) is a coronary artery disease affecting 50% of heart transplant (HTx) recipients, and it is the major cause of graft loss. CAV is driven by the interplay of immunological and non-immunological factors, setting off a cascade of events promoting endothelial damage a...

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Bibliographic Details
Main Authors: Elisa Serafini, Anna Corti, Diego Gallo, Claudio Chiastra, Xian C. Li, Stefano Casarin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
heart transplant
chronic rejection
cardiac allograft vasculopathy
arterial wall remodeling
coronary artery
computational model
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1190409/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1190409/full

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