Association of Ligamentum Flavum Hypertrophy with Adolescent Idiopathic Scoliosis Progression—Comparative Microarray Gene Expression Analysis

Association of Ligamentum Flavum Hypertrophy with Adolescent Idiopathic Scoliosis Progression—Comparative Microarray Gene Expression Analysis

The role of the ligamentum flavum (LF) in the pathogenesis of adolescent idiopathic scoliosis (AIS) is not well understood. Using magnetic resonance imaging (MRI), we investigated the degrees of LF hypertrophy in 18 patients without scoliosis and on the convex and concave sides of the apex of the cu...

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Bibliographic Details
Main Authors: Shoji Seki, Mami Iwasaki, Hiroto Makino, Yasuhito Yahara, Miho Kondo, Katsuhiko Kamei, Hayato Futakawa, Makiko Nogami, Kenta Watanabe, Nguyen Tran Canh Tung, Tatsuro Hirokawa, Mamiko Tsuji, Yoshiharu Kawaguchi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
ligamentum flavum
adolescent idiopathic scoliosis
microarray analysis
TGF-β signaling
elastic fiber
interleukin-6
Online Access:https://www.mdpi.com/1422-0067/23/9/5038

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https://www.mdpi.com/1422-0067/23/9/5038

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