Endothelial cells metabolically regulate breast cancer invasion toward a microvessel

Breast cancer metastasis is initiated by invasion of tumor cells into the collagen type I-rich stroma to reach adjacent blood vessels. Prior work has identified that metabolic plasticity is a key requirement of tumor cell invasion into collagen. However, it remains largely unclear how blood vessels...

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Bibliographic Details
Main Authors: Matthew L. Tan, Niaa Jenkins-Johnston, Sarah Huang, Brittany Schutrum, Sandra Vadhin, Abhinav Adhikari, Rebecca M. Williams, Warren R. Zipfel, Jan Lammerding, Jeffrey D. Varner, Claudia Fischbach
Format: Article
Language:English
Published: AIP Publishing LLC 2023-12-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0171109