Effect of chromosomal instability on the mutation-selection balance in unicellular populations.

This paper develops a mathematical model describing the evolutionary dynamics of a unicellular, asexually replicating population exhibiting chromosomal instability. Chromosomal instability is a form of genetic instability characterized by the gain or loss of entire chromosomes during cell division....

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Bibliographic Details
Main Authors: Eran Itan, Emmanuel Tannenbaum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3359333?pdf=render