Role of endothelial cells in graft-versus-host disease

Role of endothelial cells in graft-versus-host disease

To date, the only curative treatment for high-risk or refractory hematologic malignancies non-responsive to standard chemotherapy is allogeneic hematopoietic transplantation (allo-HCT). Acute graft-versus-host disease (GVHD) is a donor T cell-mediated immunological disorder that is frequently fatal...

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Bibliographic Details
Main Authors: Lotus Neidemire-Colley, Jérémy Robert, Antoine Ackaoui, Adrienne M. Dorrance, Martin Guimond, Parvathi Ranganathan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
endothelial cell
endotheial dysfunction
GvHD
inflammation
integrins
selectins
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1033490/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1033490/full

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