Metformin attenuates brain damage in mouse model of lipopolysaccharide-induced sepsis

Metformin attenuates brain damage in mouse model of lipopolysaccharide-induced sepsis

Objective To explore the mitigative effect of metformin on brain damage in mice with lipopolysaccharide (LPS)-induced sepsis. Methods A total of 104 male BALB/c mice were randomly divided into 4 groups (n=26), that is, control, metformin, LPS and LPS+metformin group. LPS of 20 mg/kg was intraperiton...

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Bibliographic Details
Main Authors: TIAN Jing, DONG Yan, LIU Gang, ZHANG Li, TANG Ling
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2019-08-01
Series:Di-san junyi daxue xuebao
Subjects:
metformin
inflammation
lipopolysaccharide
sepsis
brain damage
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201902108.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/201902108.htm

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