Development and preliminary assessment of a CRISPR–Cas12a-based multiplex detection of Mycobacterium tuberculosis complex

Development and preliminary assessment of a CRISPR–Cas12a-based multiplex detection of Mycobacterium tuberculosis complex

Since the onset of the COVID-19 pandemic in 2020, global efforts towards tuberculosis (TB) control have encountered unprecedented challenges. There is an urgent demand for efficient and cost-effective diagnostic technologies for TB. Recent advancements in CRISPR–Cas technologies have improved our ca...

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Bibliographic Details
Main Authors: Jing Xiao, Jieqiong Li, Shuting Quan, Yacui Wang, Guanglu Jiang, Yi Wang, Hairong Huang, Weiwei Jiao, Adong Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Mycobacterium tuberculosis complex
CRISPR-Cas12a
multiplex detection
fluorescent biosensor
lateral flow biosensor
point-of-care testing
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1233353/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1233353/full

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