RAD51 Inhibition Induces R-Loop Formation in Early G1 Phase of the Cell Cycle

RAD51 Inhibition Induces R-Loop Formation in Early G1 Phase of the Cell Cycle

R-loops are three-stranded structures generated by annealing of nascent transcripts to the template DNA strand, leaving the non-template DNA strand exposed as a single-stranded loop. Although R-loops play important roles in physiological processes such as regulation of gene expression, mitochondrial...

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Bibliographic Details
Main Authors: Zuzana Nascakova, Barbora Boleslavska, Vaclav Urban, Anna Oravetzova, Edita Vlachova, Pavel Janscak, Jana Dobrovolna
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
RAD51
R-loop
B02 inhibitor
G1 phase of the cell cycle
origin of replication
pre-replication complex
Online Access:https://www.mdpi.com/1422-0067/22/7/3740

Internet

https://www.mdpi.com/1422-0067/22/7/3740

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